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HLX1 (Q338) polyclonal antibody

货号: BS2658

价格：￥

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2658

Product Name :HLX1 (Q338) polyclonal antibody

Swiss-Prot :Q14774

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :HLX1 (homeobox protein HB24) is a 488 amino acid protein encoded by the human gene HLX1. HLX1 belongs to the H2.0 homeobox family and contains one homeobox DNA-binding domain. HLX1 is considered a diverged human homeodomain-containing protein known to be expressed in hematopoietic progenitors and activated lymphocytes. HLX1 is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. It is also involved in embryogenesis and hematopoiesis. Overexpression of HLX1 will cause a marked increase in activated T cells/thymocytes and interleukin-2 receptor expression. Overexpression will also impair the normal development of CD4+ T cells and will prevent the thymus from undergoing normal involution.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HLX1 (Q338) polyclonal antibody detects endogenous levels of HLX1 protein.

BiowMW :~ 75 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX; Homeobox protein HB24; Homeobox protein HLX1;

Immunogen :Synthetic peptide, corresponding to amino acids 303-360 of Human HLX1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HLX1 (Q338) polyclonal antibody at 1:1000 dilution Lane1:JURKAT whole cell lysate(37ug) Lane2:THP-1 whole cell lysate(37ug) Lane3:The peripheral blood cell lysate of Rat(36ug) Lane4:The peripheral blood cell lysate of Mouse(36ug)