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COX IV polyclonal antibody

货号: BS80480

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS80480

Product Name :COX IV polyclonal antibody

Swiss-Prot :P13073

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COX IV polyclonal antibody detects endogenous levels of COX IV protein.

BiowMW :17KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :COX4; Cytochrome c oxidase subunit 4 isoform 1 mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human COX IV.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of COX IV expression in mouse lung (A), mouse liver (B), rat liver (C) whole cell lysates.

Immunohistochemical analysis of COX IV staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of COX IV staining in HeLa cells.