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Ubiquitin polyclonal antibody

货号: BS80195

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS80195

Product Name :Ubiquitin polyclonal antibody

Swiss-Prot :P0CG47; P0CG48; P62979; P62987

Host :Rabbit

Reactivity :Human, Mouse, Rat, Chicken, Monkey, Pig, Rabbit

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Ubiquitin polyclonal antibody detects endogenous levels of Ubiquitin protein.

BiowMW :9KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :UBB; Polyubiquitin-B; UBC; Polyubiquitin-C; RPS27A; UBA80; UBCEP1; Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; UBA52; UBCEP2; Ubiquitin-60S ribosomal protein L40; CEP52; Ubiquitin A-52 residue ribosomal protein fusion product 1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Ubiquitin.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Ubiquitin expression in mouse liver (A), mouse testis (B), rat liver (C), rat testis (D) whole cell lysates.

Immunohistochemical analysis of Ubiquitin staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of Ubiquitin staining in HepG2 cells.