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TLR9 polyclonal antibody

货号: BS79908

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79908

Product Name :TLR9 polyclonal antibody

Swiss-Prot :Q9NR96

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200

Background :The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TLR9 polyclonal antibody detects endogenous levels of TLR9 protein

BiowMW :135KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Toll-like receptor 9; CD289

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TLR9.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of TLR9 expression in mouse spleen (A), rat spleen (B) whole cell lysates.

Immunohistochemical analysis of TLR9 staining in rat spleen formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）