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GIP polyclonal antibody

货号: BS7977

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7977

Product Name :GIP polyclonal antibody

Swiss-Prot :P09681

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200

Background :Glucose-dependent insulinotropic polypeptide (GIP) is a major physiologic factor in the augmentation of the insulin response to oral glucose. GIP is a peptide hormone that is released postprandially from the small intestine and acts in concert with glucagon-like peptide (GLP)-1 to potentiate glucose-induced insulin secretion from the pancreatic β-cell. GIP has been shown to increase adenylyl cyclase activity, elevate intracellular calcium levels, and stimulate a mitogen-activated protein kinase pathway in the pancreatic β-cell. Additionally, nutrient protein provides a potent stimulus for GIP expression, an effect that occurs at the posttranslational level and may be mediated in part through the acid-stimulatory properties of protein. GIP release is demonstrated predominantly after ingestion of carbohydrate and fat and the effects of acid on GIP are consistent with a role for GIP as an enterogastrone.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GIP polyclonal antibody detects endogenous levels of GIP protein.

BiowMW :~ 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic polypeptide; Incretin hormone

Immunogen :Recombinant full length protein of human GIP.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GIP expression in mouse small intestine (A) whole cell lysates.

Immunohistochemical analysis of GIP staining in human colon formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）