产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TNF-α polyclonal antibody

货号: BS79539

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79539

Product Name :TNF-α polyclonal antibody

Swiss-Prot :P01375

Host :Rabbit

Reactivity :Human, Mouse, Rat, Monkey, Pig

Applications :WB,IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TNF-α polyclonal Antibody detects endogenous levels of TNF-α protein.

BiowMW :~ 26, 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TNF-α.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of TNF-α expression in HEK293T (A), Hela (B), mouse lung (C), mouse kidney (D), mouse spleen (E) whole cell lysates.

Immunohistochemical analysis of TNF-α staining in human tonsil formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of TNF-α staining in HepG2 cells.

Scorpion venom heat-resistant peptide alleviates mitochondrial dynamics imbalance induced by PM2.5 exposure by downregulating the PGC-1α/SIRT3 signaling pathway

JournalToxicology Research

ApplicationWB

IF2.1

SpeciesMouse

PMID