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CAMKK2 polyclonal antibody

货号: BS79301

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79301

Product Name :CAMKK2 polyclonal antibody

Swiss-Prot :Q96RR4

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:50 - 1:200

Background :The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CAMKK2 polyclonal antibody detects endogenous levels of CAMKK2 protein.

BiowMW :65KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAMKKB; KIAA0787; Calcium/calmodulin-dependent protein kinase kinase 2; CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase kinase beta; CaMKK beta

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CAMKK2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CAMKK2 expression in mouse brain (A), rat brain (B) whole cell lysates.

Immunohistochemical analysis of CAMKK2 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of CAMKK2 staining in HepG2 cells.