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SLC7A8 polyclonal antibody

货号: BS75995

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS75995

Product Name :SLC7A8 polyclonal antibody

Swiss-Prot :Q9UHI5

Host :Rabbit

Reactivity :Human, Mouse, Rat, Rabbit

Applications :WB

Application_all :WB,1:500 - 1:1000

Background :Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (reabsorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC7A8 polyclonal antibody detects endogenous levels of SLC7A8 protein.

BiowMW :65kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LAT2; Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LAT2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of SLC7A8 expression in HEK293T (A), HepG2 (B), mouse kidney (C), rat brain (D) whole cell lysates.