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FBXO32 polyclonal antibody

货号: BS7435

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7435

Product Name :FBXO32 polyclonal antibody

Swiss-Prot :Q969P5

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FBXO32 polyclonal antibody detects endogenous levels of FBXO32 protein.

BiowMW :42KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :F-box only protein 32; Atrogin-1; Muscle atrophy F-box protein; MAFbx

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human FBXO32.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of FBXO32 expression in mouse muscle (A), rat muscle (B) whole cell lysates.

Immunofluorescent analysis of FBXO32 staining in Hela cells.

免疫沉淀（IP）

免疫组织化学（IHC）