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PTPN22 polyclonal antibody

货号: BS6794

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS6794

Product Name :PTPN22 polyclonal antibody

Swiss-Prot :Q9Y2R2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:200

Background :This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PTPN22 polyclonal Antibody detects endogenous levels of PTPN22 protein.

BiowMW :~ 98 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTPN8; Tyrosine-protein phosphatase non-receptor type 22; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; LyP; PEST-domain phosphatase; PEP

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PTPN22.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PTPN22 expression in Jurkat (A), K562 (B), C6 (C), BV2 (D) whole cell lysates.

Immunohistochemical analysis of PTPN22 staining in human aratracheal lymph nodes formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of PTPN22 staining in MCF7 cells.