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Collagen 2 alpha 1 polyclonal antibody

货号: BS66281

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66281

Product Name :Collagen 2 alpha 1 polyclonal antibody

Swiss-Prot :P02458

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Collagen 2 alpha 1 polyclonal antibody detects endogenous levels of Collagen 2 alpha 1 protein.

BiowMW :~ 112, 96 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Collagen alpha-1(II) chain; Alpha-1 type II collagen

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Collagen 2 alpha 1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Collagen 2 alpha 1 expression in C6 (A), AML12 (B), SGC7901 (C), A375 (D) whole cell lysates.

Immunohistochemical analysis of Collagen 2 alpha 1 staining in human liver cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of Collagen 2 alpha 1 staining in MCF7 cells.

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