Product Name :GPR19 polyclonal antibody
Reactivity :Human,Mouse,Rat,Monkey
Applications :WB, IF/ICC,IHC
Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200|IHC,1:50 - 1:100
Background :G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. GPR19, an orphan receptor, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of adult mouse brain, including the olfactory bulb, the hippocampus, hypothalamic nuclei and the cerebellum.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GPR19 polyclonal antibody detects endogenous levels of GPR19 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Probable G-protein coupled receptor 19; GPR-NGA
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GPR19.
