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CD117 (1A9) monoclonal antibody

货号: MB8588

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB8588

Product Name :CD117 (1A9) monoclonal antibody

Swiss-Prot :P10721

Host :Mouse

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD117 (1A9) monoclonal antibody detects endogenous levels of CD117 protein.

BiowMW :~ 46 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor-Infiltrating Immune Cell Marker Guide,

Alternative Name :Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; KIT; SCFR

Immunogen :Synthetic peptide, corresponding to amino acids Human CD117.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD117 (1A9) mAb at 1:1000 dilution Lane1:Hela whole cell lysate(40ug) Lane2:The Testis tissue lysate of Mouse(40ug) Lane3:The Testis tissue lysate of Rat(40ug) Lane4:Jurkat whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug)

Comparative study of the laxative effects of konjac oligosaccharides and konjac glucomannan on loperamide-induced constipation in rats

JournalFood & Function

ApplicationWB

IF5.396

SpeciesRat

PMID34286775