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CD161 (3F8) monoclonal antibody（KU）

货号: MB8565

价格：￥ 1350

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :MB8565

Product Name :CD161 (3F8) monoclonal antibody（KU）

Swiss-Prot :Q12918

Host :Mouse

Reactivity :Rat

Applications :WB

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :Natural killer (NK) and T cells express a superfamily of proteins with structural features of C-type lectins. T cells bearing natural killer receptors (NKRs) such as CD94 and CD161 are present in psoriasis. CD161 mediates NK cell activation and functions as an activating receptor. CD161 is a prototypic marker of NK cells, although it is also found on a subset of CD8+ T cells. The expression of NK receptors on CD8+ T cells can be considered a marker of cytotoxic effector T cells that are expanded in vivo after antigenic activation leading to extensive proliferation. The transcription, mRNA accumulation, and surface expression of CD161, a molecule involved in triggering cytotoxicity, is specifically upregulated by IL-12.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD161 (3F8) mAb detects endogenous levels of CD161 protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD161

Immunogen :Synthetic peptide, corresponding to amino acids of Human CD161.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD 161(NKR-PIA) mAb at 1:2000 dillution Lane1:The Peripheral blood lysate of Rat(40μg) Lane2:The Liver tissue lysate of Rat(40μg)