产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

PURB monoclonal antibody

货号: MB67177

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB67177

Product Name :PURB monoclonal antibody

Swiss-Prot :Q96QR8

Host :Mouse

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/4000)

Background :Purβ (purine-rich element-binding protein B), also known as transcriptional activator protein Purβ, is a 312 amino acid protein that belongs to the PUR DNA-binding protein family. The Purβ gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, the Purβ protein is implicated in the control of both DNA replication and transcription. Deletion of the Purβ gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia (AML), which is a malignant disease where in hematopoietic precursors are arrested in an early stage of development. Localizing to nucleus, the Purβ protein is expressed in myocardium of heart failure patients. The Purβ gene is conserved in mouse, rat, zebrafish, fruit fly, mosquito, C. elegans, A. thaliana and rice. and maps to human chromosome 7p13.

Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PURB protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Transcriptional activator protein Pur-beta; Purine-rich element-binding protein B

Immunogen :Recombinant fusion protein of human PURB. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PURB expression in Jurkat (A), HeLa (B), NCIH460 (C), HepG2 (D), MCF7 (E), NIH3T3 (F) whole cell lysates.

免疫沉淀（IP）