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PNOC monoclonal antibody

货号: MB67092

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB67092

Product Name :PNOC monoclonal antibody

Swiss-Prot :Q13519

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/4000)

Background :Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (k-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a k opioid peptide, Nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.

Product :Mouse IgG2b kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PNOC protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OFQ; Prepronociceptin

Immunogen :Recombinant fusion protein of human PNOC. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PNOC expression in PNOC recombinant protein (A) whole cell lysates.

免疫沉淀（IP）