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TLE1 monoclonal antibody

货号: MB67073

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB67073

Product Name :TLE1 monoclonal antibody

Swiss-Prot :Q04724

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors, such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.

Product :Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TLE1 protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Wntβ catenin signaling

Alternative Name :Transducin-like enhancer protein 1; E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TLE1. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TLE1 expression in A549 (A) whole cell lysates.