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HMGA2 monoclonal antibody

货号: MB67017

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB67017

Product Name :HMGA2 monoclonal antibody

Swiss-Prot :P52926

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/4000)

Background :HMGA2 belongs to the family of high mobility group with AT-hook DNA binding domain. HMGA proteins are considered architectural transcription factors; they do not have direct transcriptional activation capacity, but instead regulate gene expression by changing DNA conformation through binding to AT-rich regions in the DNA and/or direct interaction with other transcription factors . HMGA2 is abundantly and ubiquitously expressed and plays a crucial role during embryonic development . HMGA2 promotes stem cell self-renewal and research studies have shown that decreased HMGA2 expression is associated with stem cell aging . Investigators have shown that expression levels of HMGA2 are very low in normal adult tissues, while either overexpression or rearrangement is associated with many types of cancer .

Product :Mouse IgG2b. Supplied in crude ascites with 0.01% sodium azide.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HMGA2 protein.

BiowMW :~ 18 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HMGIC; High mobility group protein HMGI-C; High mobility group AT-hook protein 2

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HMGA2. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HMGA2 expression in HepG2 (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）