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Hexokinase 2 monoclonal antibody

货号: MB67016
价格 1350
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :MB67016
Product Name :Hexokinase 2 monoclonal antibody
Swiss-Prot :P52789
Host :Mouse
Reactivity :Human
Applications :WB
Application_all :WB (1/1000 - 1/2000), IHC (1/50 - 1/200)
Background :Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation .
Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :This antibody is purified through a protein G column.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of Hexokinase 2 protein.
BiowMW :~ 105 kDa
Note :For research use only, not for use in diagnostic procedure.
Pathway :Warburg Effect.
Alternative Name :Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase
Immunogen :Recombinant fusion protein of human Hexokinase 2. The exact sequence is proprietary.
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of Hexokinase 2 expression in Hela (A), 293 (B), Jurkat (C) whole cell lysates.
Immunohistochemical analysis of Hexokinase 2 staining in human Skeletal muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com