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Caspase 3 monoclonal antibody

货号: MB66984

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66984

Product Name :Caspase 3 monoclonal antibody

Swiss-Prot :P42574

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Caspase-3 (CPP-32, Apopain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) . Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position .

Product :Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Caspase 3 protein.

BiowMW :~ 31 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer\'s Disease,Regulation of Apoptosis,Death Receptor Signaling,ErbB HER Signaling,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis.

Alternative Name :CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1

Immunogen :Recombinant fusion protein of human Caspase 3. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Caspase 3 expression in Jurkat (A), Ramos (B) whole cell lysates.