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VEGFR3 monoclonal antibody

货号: MB66974

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66974

Product Name :VEGFR3 monoclonal antibody

Swiss-Prot :P35916

Host :Mouse

Reactivity :Human

Applications :WB, FC

Application_all :WB (1/500 - 1/1000)

Background :Vascular endothelial growth factor receptor 3 (VEGFR3) is a 195 kDa membrane receptor tyrosine kinase. VEGF receptors are characterized by the presence of seven extracellular immunoglobulin (Ig)-like domains followed by a membrane-spanning domain and a conserved intracellular tyrosine kinase domain . VEGF receptor 3 expression is largely restricted to adult lymphatic endothelium and is thought to control lymphangiogenesis . Binding of VEGF-C/VEGF-D to VEGFR3 results in transphosphorylation of tyrosine residues in its intracellular domain, recruitment of signaling molecules and activation of ERK1/2 and Akt signaling cascades .

Product :Mouse IgG2a. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of VEGFR3 protein.

BiowMW :~ 175 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VEGFR3; Vascular endothelial growth factor receptor 3; VEGFR-3; Fms-like tyrosine kinase 4; FLT-4; Tyrosine-protein kinase receptor FLT4

Immunogen :Recombinant fusion protein of human VEGFR3. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of VEGFR3 expression in A549 (A), 293T (B) whole cell lysates.