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HGF monoclonal antibody

货号: MB66884

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66884

Product Name :HGF monoclonal antibody

Swiss-Prot :P14210

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :The Hepatocyte Growth Factor was initially discovered as a mitogenic cytokine that induced hepatocyte replication and proliferation . HGF is produced by stromal cells where it is processed by extracellular serine proteases into a heterodimer consisting of alpha and beta subunits .Through activation of its receptor, cMET, HGF has a wide range of effects beyond hepatocytes that includes angiogenesis, epithelial cell proliferation and morphogenesis, and tissue protection and regeneration . The HGF-cMET axis has been associated with several diseases, including cancer, where HGF has been shown to promote invasion, metastasis, and drug resistance . These research studies suggest that HGF is a potential diagnostic and therapeutic target.

Product :Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HGF protein.

BiowMW :~ 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HPTA; Hepatocyte growth factor; Hepatopoietin-A; Scatter factor; SF

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HGF. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HGF expression in HepG2 (A), Ramos (B) whole cell lysates.

免疫沉淀（IP）