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S100-B monoclonal antibody

货号: MB66795

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66795

Product Name :S100-B monoclonal antibody

Swiss-Prot :P50114

Host :Mouse

Reactivity :Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 a and b, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin a and parvalbumin b (also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 a chain and S-100 b chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two a chains, two b chains or one a and one b chain. S-100 localizes to the cytoplasm and nuclei of astrocytes, Schwann’s cells, ependymomas and astrogliomas. S-100 is also detected in almost all benign naevi, malignant melanocytic tumours and in Langerhans cells in the skin. Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 a and b are present in a variety of other tissues, and calbindin is present in intestine and kidney.

Product :Mouse IgM kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of S100-B protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B

Immunogen :Recombinant fusion protein of human S100-B. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of S100-B expression in mouse liver (A) whole cell lysates.

免疫沉淀（IP）