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CD31 Rabbit monoclonal antibody

货号: MB66327

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66327

Product Name :CD31 Rabbit monoclonal antibody

Swiss-Prot :P16284

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF/ICC IP

Application_all :WB: 1:500~1:2000 IHC: 1:100~1:300 IF/ICC: 1:100~1:300 IP: 1:50~1:100

Background :CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD31 Rabbit monoclonal antibody detects endogenous levels of CD31 protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD31

Immunogen :Recombinant fusion protein of human CD31.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CD31 expression in HepG2 (A), mouse brain (B), rat spleen (C) whole cell lysates.

Immunohistochemical analysis of CD31 staining in human tonsil formalin fixed paraffin embedded tissue section.