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TDG mouse monoclonal antibody (KU)

货号: MB4503

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :MB4503

Product Name :TDG mouse monoclonal antibody (KU)

Swiss-Prot :Q13569

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :IHC, WB

Application_all :WB 1:2000, IHC 1:150

Background :The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2b

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of LGALS9 mouse monoclonal antibody at 1:500 dilution. Lane1:THP-1 whole cell lysate(30ug)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, )