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LMNA mouse monoclonal antibody (KU)

货号: MB4444

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :MB4444

Product Name :LMNA mouse monoclonal antibody (KU)

Swiss-Prot :P02545

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :IF, WB

Application_all :WB 1:2500~5000, IF 1:50~100

Background :The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit (DFF-45); Inhibitor of CAD (ICAD)

Immunogen :Full length human recombinant protein of human DFFA (NP_004392) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of DFF45 (ICAD) mouse monoclonal antibody at 1:500 dilution. Lane1:A549 whole cell lysate(30ug)

Anti-DFFA mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DFFA (RC202879).

免疫沉淀（IP）

免疫组织化学（IHC）