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IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody (KU)

货号: MB4392

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :MB4392

Product Name :IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody (KU)

Swiss-Prot :O75874

Host :Mouse

Reactivity :Human, Dog, Rat, Mouse

Applications :IHC, WB

Application_all :WB 1:2000, IHC 1:150

Background :Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2b

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of LGALS9 mouse monoclonal antibody at 1:500 dilution. Lane1:THP-1 whole cell lysate(30ug)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, )