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NFKBIA mouse monoclonal antibody (KU)

货号: MB4382

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :MB4382

Product Name :NFKBIA mouse monoclonal antibody (KU)

Swiss-Prot :P25963

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :IF, IHC, WB

Application_all :WB 1:200, IHC 1:150, IF 1:100

Background :This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :E3 ubiquitin-protein ligase TRIM38; EC:2.3.2.27; RING finger protein 15; Tripartite motif-containing protein 38 ; Zinc finger protein RoRet; TRIM38

Immunogen :Human recombinant protein fragment corresponding to amino acids 1-265 of human TRIM38(NP_006346) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of TRIM38 mouse monoclonal antibody at 1:500 dilution. Lane1:HepG2 whole cell lysate(30ug)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TRIM38 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min)

Anti-TRIM38 mouse monoclonal antibodyimmunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TRIM38 (RC201944).