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CTNNB1 mouse monoclonal antibody (KU)

货号: MB4261

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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详细信息检测数据实验指南文献

No. :MB4261

Product Name :CTNNB1 mouse monoclonal antibody (KU)

Swiss-Prot :P35222

Host :Mouse

Reactivity :Human, Dog, Rat, Monkey, Mouse

Applications :FC, IF, WB

Application_all :WB 1:500~1000, IF 1:100, FLOW 1:100

Background :The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :von Willebrand factor A domain-containing protein 5A; Breast cancer suppressor candidate 1 (BCSC-1); Loss of heterozygosity 11 chromosomal region 2 gene A protein; VWA5A; BCSC1; LOH11CR2A

Immunogen :Full length human recombinant protein of human VWA5A(NP_055437) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of VWA5A mouse monoclonal antibody at 1:5000 dilution Lane1:PC12 whole cell lysate(30ug) Lane2:COS-7 whole cell lysate(30ug) Lane3:Hela whole cell lysate(30ug)

Anti-VWA5A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY VWA5A.

Metabolomics Analysis of Functional Activity Changes in Residual Tumour Cells After IOCS Treatment

JournalJOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ApplicationWB

IF4.3

SpeciesHuman

PMID40111872