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MAPK7 (ERK5) mouse monoclonal antibody (KU)

货号: MB4240

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :MB4240

Product Name :MAPK7 (ERK5) mouse monoclonal antibody (KU)

Swiss-Prot :Q13164

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :FC, IF, WB

Application_all :WB 1:500~1000, IF 1:100, FLOW 1:100

Background :The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :von Willebrand factor A domain-containing protein 5A; Breast cancer suppressor candidate 1 (BCSC-1); Loss of heterozygosity 11 chromosomal region 2 gene A protein; VWA5A; BCSC1; LOH11CR2A

Immunogen :Full length human recombinant protein of human VWA5A(NP_055437) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of VWA5A mouse monoclonal antibody at 1:5000 dilution Lane1:PC12 whole cell lysate(30ug) Lane2:COS-7 whole cell lysate(30ug) Lane3:Hela whole cell lysate(30ug)

Anti-VWA5A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY VWA5A.