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PEX5 mouse monoclonal antibody (KU)

货号: MB4205

价格：￥ 398

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

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No. :MB4205

Product Name :PEX5 mouse monoclonal antibody (KU)

Swiss-Prot :P50542

Host :Mouse

Reactivity :Human, Dog, Rat, Monkey, Mouse

Applications :FC, IF, WB

Application_all :WB 1:500~1000, IF 1:100, FLOW 1:100

Background :The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :von Willebrand factor A domain-containing protein 5A; Breast cancer suppressor candidate 1 (BCSC-1); Loss of heterozygosity 11 chromosomal region 2 gene A protein; VWA5A; BCSC1; LOH11CR2A

Immunogen :Full length human recombinant protein of human VWA5A(NP_055437) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of VWA5A mouse monoclonal antibody at 1:5000 dilution Lane1:PC12 whole cell lysate(30ug) Lane2:COS-7 whole cell lysate(30ug) Lane3:Hela whole cell lysate(30ug)

Anti-VWA5A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY VWA5A.