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HP1 alpha (1E8) monoclonal antibody

货号: MB3305

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB3305

Product Name :HP1 alpha (1E8) monoclonal antibody

Swiss-Prot :P45973

Host :Mouse

Reactivity :Human,Rat,Mouse

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :Calculated MW: 22 kDa; Observed MW: 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha

Immunogen :Purified recombinant protein expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using HP1 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Human tonsils using HP1 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.