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LC3A (8F5) monoclonal antibody

货号: MB3283

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB3283

Product Name :LC3A (8F5) monoclonal antibody

Swiss-Prot :Q9H492

Host :Mouse

Reactivity :Human,Rat,Mouse

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :Calculated MW: 14 kDa; Observed MW: 14,16 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha

Immunogen :Purified recombinant protein expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LC3A in Hela lysates, 3T3 lysates, rat Brain lysates using LC3A antibody.

Immunohistochemistry analysis of paraffin-embedded Human Heptacarcinoma Tissue using LC3A antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.