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Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) monoclonal antibody

货号: MB3271

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB3271

Product Name :Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) monoclonal antibody

Swiss-Prot :P27361/P28482

Host :Mouse

Reactivity :Human,Rat,Mouse

Applications :IHC-P

Application_all :IHC: 1/50-1/100

Background :Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :-

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MAPK1/MAPK3

Immunogen :Synthetic peptide conjugated to KLH.

Conjugate :Unconjugated

Modification :Phosphorylated

Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.