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Phospho-AKT (Ser473) (8A9) monoclonal antibody

货号: MB3262

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB3262

Product Name :Phospho-AKT (Ser473) (8A9) monoclonal antibody

Swiss-Prot :P31749

Host :Mouse

Reactivity :Human

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :Calculated MW: 56 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha

Immunogen :Synthetic peptide conjugated to KLH.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-AKT in PC-3 lysates using Phospho-AKT antibody.

Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using Phospho-Akt Ser473 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.