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CD45 (8C1) monoclonal antibody

货号: MB3167

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB3167

Product Name :CD45 (8C1) monoclonal antibody

Swiss-Prot :P06800

Host :Mouse

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :Calculated MW: 145 kDa; Observed MW: 145 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GP180; L CA; CD45 antigen

Immunogen :Synthetic Peptide of CD45

Conjugate :Unconjugated

Modification :Unmodified

Immunofluorescence analysis of CD45 in Human livercancer tissue using CD45 antibody,and DAPI .

Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.

Western blot analysis of CD45 in Jurkat lysates using CD45 antibody.