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Bax (2B12) monoclonal antibody

货号: MB3042

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB3042

Product Name :Bax (2B12) monoclonal antibody

Swiss-Prot :Q07812

Host :Mouse

Reactivity :Human,Monkey

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2a

BiowMW :Calculated MW: 21 kDa; Observed MW: 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Immunogen :Purified recombinant human Bax protein fragments expressed in E.coli

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Bax in COS7, Raji, CEM and Hela lysates using Bax antibody.

免疫沉淀（IP）