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HDAC6 (3B2) monoclonal antibody

货号: MB3031

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB3031

Product Name :HDAC6 (3B2) monoclonal antibody

Swiss-Prot :Q9UBN7

Host :Mouse

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2a

BiowMW :Calculated MW: 131 kDa; Observed MW: 160 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Immunogen :Purified recombinant human HDAC6 protein expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HDAC6 in T47D, Jurkat CHO-K1 and CHO-K1 transfected by HDAC6fragment EGFP fusion protein lysates using HDAC6 antibody.

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