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beta Arrestin 1 (6A1) monoclonal antibody

货号: MB3022

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB3022

Product Name :beta Arrestin 1 (6A1) monoclonal antibody

Swiss-Prot :P49407

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2b

BiowMW :Calculated MW: 47 kDa; Observed MW: 51 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.

Immunogen :Recombinant human β-Arrestin 1 protein.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of betaArrestin 1 in K562 and Hela lysates using betaArrestin 1 antibody.

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