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HDAC2 (2D9) monoclonal antibody

货号: MB3020

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB3020

Product Name :HDAC2 (2D9) monoclonal antibody

Swiss-Prot :Q92769

Host :Mouse

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2b

BiowMW :Calculated MW: 55 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HDAC2; Histone deacetylase 2; HD2

Immunogen :Purified recombinant human HDAC2 protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HDAC2 in THP-1, SH-SY5Y, K562, COS7, C6, 3T3 and Hela lysates using HDAC2 antibody.

免疫沉淀（IP）