Product Name :Rad9 monoclonal antibody
Reactivity :Human,Mouse,Rat,Monkey
Application_all :WB: 1/500-1/1000 IP: 1/20
Background :This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 43 kDa; Observed MW: 55 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RAD9; hRAD9
Immunogen :Purified recombinant human RAD9A protein fragments expressed in E.coli
