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PKC beta 2 monoclonal antibody

货号: MB12315

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB12315

Product Name :PKC beta 2 monoclonal antibody

Swiss-Prot :P05771

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 77 kDa; Observed MW: 77 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta

Immunogen :A synthesized peptide derived from human PKC beta 2

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of PKC beta 2 in K562 using PKC beta 2 antibody,and DAPI.

Western blot analysis of PKC beta 2 in rat brain lysates using PKC beta 2 antibody.Observed band size:77kDa.