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Tuberin monoclonal antibody

货号: MB12288

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB12288

Product Name :Tuberin monoclonal antibody

Swiss-Prot :P49815

Host :Rabbit

Reactivity :Human

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 201 kDa; Observed MW: 201 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4

Immunogen :Recombinant protein of human Tuberin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Tuberin in Hela, A549, HL-60, U2OS lysates using Tuberin antibody.

免疫沉淀（IP）