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Rad21 monoclonal antibody

货号: MB12218

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB12218

Product Name :Rad21 monoclonal antibody

Swiss-Prot :O60216

Host :Rabbit

Reactivity :Human,Hamster

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 72 kDa; Observed MW: 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog

Immunogen :A synthetic peptide of human Rad21

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of Rad21 in Hela using Rad21 antibody,and DAPI.

Western blot analysis of Rad21 in Hela, CHO-K1, Ramos lysates using Rad21 antibody.