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PRAS40 monoclonal antibody

货号: MB12204

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB12204

Product Name :PRAS40 monoclonal antibody

Swiss-Prot :Q96B36

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 27 kDa; Observed MW: 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate

Immunogen :A synthetic peptide of human PRAS40

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PRAS40 in Hela, A549, C6 lysates using PRAS40 antibody.

免疫沉淀（IP）