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p57 Kip2 monoclonal antibody

货号: MB12177

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB12177

Product Name :p57 Kip2 monoclonal antibody

Swiss-Prot :P49918

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 32 kDa; Observed MW: 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2

Immunogen :A synthetic peptide of human p57 Kip2

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of p57 Kip2 in A549, U2OS lysates using p57 Kip2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p57 Kip2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.