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MERTK monoclonal antibody

货号: MB12121

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB12121

Product Name :MERTK monoclonal antibody

Swiss-Prot :Q12866

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 110 kDa; Observed MW: 210 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Immunogen :A synthetic peptide of human MERTK

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MERTK in MCF-7, 293T lysates using MERTK antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using MERTK antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.