产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Lamin A/C monoclonal antibody

货号: MB12098

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB12098

Product Name :Lamin A/C monoclonal antibody

Swiss-Prot :P02545

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 74 kDa; Observed MW: 74,63 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LMNA; LMN1; Prelamin-A/C

Immunogen :A synthetic peptide of human Lamin A/C

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of Lamin A/C in Hela using Lamin A/C antibody,and DAPI.

Western blot analysis of Lamin A/C in 3T3, C2C12 lysates using Lamin A/C antibody.