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HIF1 beta monoclonal antibody

货号: MB12059

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB12059

Product Name :HIF1 beta monoclonal antibody

Swiss-Prot :P27540

Host :Rabbit

Reactivity :Human,Mouse,Rat,Hamster

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 87 kDa; Observed MW: 87 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta

Immunogen :Recombinant protein of human HIF1 beta

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HIF1 beta in Raw264.7, 3T3 lysates using HIF1 beta antibody.

Western blot analysis of HIF1 beta in Hela, CHO-K1, C6, Ramos lysates using HIF1 beta antibody.