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Cyclin H monoclonal antibody

货号: MB11988

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB11988

Product Name :Cyclin H monoclonal antibody

Swiss-Prot :P51946

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 38 kDa; Observed MW: 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CCNH; Cyclin-H; MO15-associated protein; p34; p37

Immunogen :A synthetic peptide of human Cyclin H/p34

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of Cyclin H in Hela using Cyclin H antibody,and DAPI.

免疫沉淀（IP）